SHANDONG MINJI CHEMICAL CO.,LTD

Chloroacetic acid,Website:http://www.minjichemical.com, industrially known as?monochloroacetic acid (MCA)?is the?organochlorine compound?with the formula ClCH2CO2H. This?carboxylic acidis a useful building-block in?organic synthesis.Illustrative of its usefulness in organic chemistry is the?O-alkylation ofsalicylaldehyde?with chloroacetic acid, followed by?decarboxylation?of the resulting?ether, producing?benzofuran.In industry, chloroacetic acid is used in the production of a wide variety of useful compounds; e.g., drugs, dyes, pesticides.?Most reactions take advantage of the high reactivity of the C?Cl bond. It is the precursor to the herbicide?glyphosate, and the?MCPA?(2-methyl-4-chlorophenoxyacetic acid) and?dimethoate?are prepared by alkylation with chloroacetic acid. Chloroacetic acid is converted to?chloroacetyl chloride, a precursor to?adrenaline?(epinephrine). Displacement of chloride by sulfide gives?thioglycolic acid, which is used as a stabilizer in?PVC?and a component in some?cosmetics.In its largest-scale application, chloroacetic acid is used to prepare the thickening agent?carboxymethyl cellulose?and?carboxymethyl starch.

•