SHANDONG MINJI CHEMICAL CO.,LTD

Dimethylpropanoic?is a?carboxylic acid?with a molecular formula of (CH3)3CCO2H. This colourless,Website:http://www.minjichemical.com, odiferous?organic compound?is solid at room temperature.Industrial routePivalic acid is prepared by"hydrocarboxylation"of?isobutene?via the?Koch reaction:(CH3)2C=CH2?+ CO + H2O ? (CH3)3CCO2HSuch reactions require an acid?catalyst?such as?hydrogen fluoride.?tert-Butyl alcohol?and?isobutyl alcohol?can also be used in place of isobutene. Globally, several million kilograms are produced annually.?Pivalic acid is also economically recovered as a by-product from the production of semi-synthetic penicillins like ampicillin and amoxycillin.Laboratory methodsIt was originally prepared by the oxidation of?pinacolone?with?chromic acid and by the hydrolysis of?tert-butyl cyanide.?Convenient laboratory routes proceed via?t-butyl chloride?via carbonation of the?Grignard reagent?and by oxidation of?pinacolone.

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